Primary Identifier | MGI:3775386 | Allele Type | Targeted |
Gene | Myc | Transmission | Germline |
Strain of Origin | 129S6/SvEvTac | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The gene locus was chosen due to its active transcription throughout T- and B- cell development. Germ-line Dbeta1 and Jbeta1.1 segments, their recombination signaling sequences and intervening intronic sequence were inserted between exon 1 and 2 of the gene locus. Southern blot analysis of T and B cells revealed germ-line and recombined versions of the knocked in gene segment. |