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Allele : Afg3l2<Emv66> AFG3-like AAA ATPase 2; endogenous ecotropic MuLV 66

Primary Identifier  MGI:3775617 Attribute String  Null/knockout
Gene  Afg3l2 Inheritance Mode  Recessive
Strain of Origin  MEV/2Ty-Afg3l2<Emv66> Is Recombinase  false
Is Wild Type  false
molecularNote  An ecotropic murine leukemia proviral reinsertion occurred within intron 14 of the gene. RT-PCR analysis on several tissues showed that no transcript containing sequences derived from exon 13-15 is expressed from this allele. An aberrant transcript contaning sequences upstream of the insertion site is detectable. Western blot analysis on tissue mitochondrial preparations shows that the protein product is not detectable in homozygous mice.
  • mutations:
  • Viral insertion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

10 Publication categories