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Allele : Ldlr<tm1(AFP)Alb> low density lipoprotein receptor; targeted mutation 1, Arthur L Beaudet

Primary Identifier  MGI:3775950 Allele Type  Targeted
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Ldlr
Transmission  Germline Strain of Origin  129S7/SvEvBrd-Hprt1<b-m2>
Is Recombinase  false Is Wild Type  false
molecularNote  A cassette containing a splice acceptor, IRES, human AFP and a splice donor was inserted into intron 1 along with a floxed neo cassette. The neo cassette was removed by transient cre expression. Expression of AFP was confirmed by a quantitative immunoassay.
  • mutations:
  • Insertion
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

1 Driven By

4 Publication categories