Primary Identifier | MGI:3775950 | Allele Type | Targeted |
Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Ldlr |
Transmission | Germline | Strain of Origin | 129S7/SvEvBrd-Hprt1<b-m2> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A cassette containing a splice acceptor, IRES, human AFP and a splice donor was inserted into intron 1 along with a floxed neo cassette. The neo cassette was removed by transient cre expression. Expression of AFP was confirmed by a quantitative immunoassay. |