| Primary Identifier | MGI:3775954 | Allele Type | Gene trapped |
| Attribute String | Hypomorph, Reporter | Gene | Wwox |
| Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A gene trap vector containing a beta-geo cassette was inserted into intron 4 and resulted in a fusion protein at exon 4. Real-time PCR shows that mRNA levels are reduced by 95% in embryos and 85-95% in adults, depending on tissue examined. Protein is undetectable in most adult tissues, however, low levels are detected in testes. This is a hypomorph. |
