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Allele : Lepr<tm2(cre)Rck> leptin receptor; targeted mutation 2, Jeffrey M Friedman
Primary Identifier  MGI:3776158 Allele Type  Targeted
Attribute String  Recombinase Gene  Lepr
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  true Is Wild Type  false
molecularNote  A cre recombinase expression cassette containing an IRES domain and a FRT-flanked neomcyin cassette was placed immediately downstream of the stop codon for the gene. Flp-mediated recombination removed the FRT-flanked neo cassette. Cre expression in the hypothalamus was confirmed by use of a virus containing a cre-dependent reporter gene.
  • mutations:
  • Insertion
  • synonyms:
  • Lepr<cre>,
  • Obrb-IRES-Cre,
  • ObRb-Cre,
  • Lepr<cre>,
  • LeprB-Cre,
  • Obrb-IRES-Cre,
  • LepRb<Cre>,
  • LepRb-IRES-Cre,
  • LeprB-Cre,
  • ObRb-Cre,
  • LepRb<Cre>,
  • LepRb-IRES-Cre
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

1 Driven By

159 Publication categories





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