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Allele : Phex<tm1.1Mkd> phosphate regulating endopeptidase homolog, X-linked; targeted mutation 1.1, Marc K Drezner

Primary Identifier  MGI:3775078 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Phex
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 17 was flanked with a loxP site and a floxed neo cassette via homologous recombination. The neo cassette was subsequently removed via in vivo Cre-mediated recombination leaving exon 17 flanked by 2 single loxP sites. Cre mediated removal of exon 17 will result in a frameshift, premature termination codon and truncated protein.
  • mutations:
  • Insertion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

4 Publication categories