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Allele : Myh7<tm1Unc> myosin, heavy polypeptide 7, cardiac muscle, beta; targeted mutation 1, University of North Carolina

Primary Identifier	MGI:3776012	Allele Type	Targeted
Attribute String	Null/knockout, Reporter	Gene	Myh7
Transmission	Germline	Strain of Origin	129P2/OlaHsd
Is Recombinase	false	Is Wild Type	false

molecularNote

Coding seqeunce for YFP was knocked-in into beta MHC gene at the translational start site to produce an allele that expresses YFP fused to the native beta MHC protein.

mutations:
Insertion

cellLines:
Not Specified

synonyms:
betaMHC-YFP,
YFP-betaMHC,
betaMHC-YFP,
YFP-betaMHC

earliestPublication:
Pandya K, et al. (2006) Fibrosis, not cell size, delineates beta-myosin heavy chain reexpression during cardiac hypertrophy and normal aging in vivo. Proc Natl Acad Sci U S A 103(45):16864-9

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

7 Publication categories

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