| Primary Identifier | MGI:3778905 | Allele Type | Targeted |
| Attribute String | Inserted expressed sequence | Gene | Gt(ROSA)26Sor |
| Transmission | Germline | Strain of Origin | 129S4/SvJae |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A Tfrc cDNA containing a point mutation that resulted in the amino acid substitution of alanine for arginine at position 654 (R654A) was knocked into the ROSA locus along with a floxed neo cassette. The neo cassette was subsequently removed by germ-line, cre-mediated recombination. This point mutation prevents binding to Tf but does not alter the interaction with Hfe. |
