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Allele : Tg(CD34)29Dgt transgene insertion 29, Daniel G Tenen

Primary Identifier  MGI:3776897 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(CD34)29Dgt
Strain of Origin  FVB/N Is Recombinase  false
Is Wild Type  false
description  Two other founder lines (lines 8 and 14) were created with one copy of the transgene inserting for each.
molecularNote  A linearized PAC clone containing the human CD34 gene and 110 kb of promoter sequence and 26 kb of downstream sequence was used as a transgene. Two copies of the transgene inserted and expression was detected in numerous tissues with highest levels detected in the bladder, heart, lymph nodes, and lungs. Expression at the RNA and protein levels was very similar to the endogenous mouse Cd34 gene.
  • mutations:
  • Insertion
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories