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Allele : Tg(CD34-tTA,-CD34)1Dgt transgene insertion 1, Daniel G Tenen

Primary Identifier	MGI:3776898	Allele Type	Transgenic
Attribute String	Inserted expressed sequence, Transactivator	Gene	Tg(CD34-tTA,-CD34)1Dgt
Strain of Origin	FVB/N	Is Recombinase	false
Is Wild Type	false

molecularNote

110 kb of human CD34 promoter sequence was placed upstream of a tTA tetracycline transactivator gene followed by an IRES domain and the coding genomic sequence for human CD34. Expression of both genes was detected in numerous tissues including heart and bone marrow.

mutations:
Insertion

synonyms:
CD34tTA,
CD34tTA

earliestPublication:
Radomska HS, et al. (2002) Transgenic targeting with regulatory elements of the human CD34 gene. Blood 100(13):4410-9

1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

5 Publication categories

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