Primary Identifier | MGI:3777275 | Allele Type | Transgenic |
Attribute String | Inducible, Recombinase | Gene | Tg(Neurog1-cre/ERT2)1Good |
Strain of Origin | C57BL/6 | Induced With | tamoxifen |
Is Recombinase | true | Is Wild Type | false |
molecularNote | A transgene was constructed where cre recombinase fused to the ligand-binding domain of a mutant human estrogen receptor was placed under the control of the upstream promoter and the downstream untranslated region of the Neurog1 gene. Cre activity was detected in cochlear ganglion neurons of transgenic mice when crossed with a cre-reporter strain and dosing with tamoxifen. |