Primary Identifier | MGI:3777464 | Allele Type | Chemically induced (ENU) |
Gene | Mycbp2 | Inheritance Mode | Recessive |
Strain of Origin | (BALB/c x C57BL/6)F1 X DBA/2J | Is Recombinase | false |
Is Wild Type | false |
description | ENU exposed DBA/2J males were mated with (BALB/c x C57BL/6)F1 females carrying the Tg(Isl1-EGFP*)1Slp reporter. |
molecularNote | ENU mutagenesis induced an G to T transition in exon 63 that resulted in a premature termination codon. The presence of a truncated protein lacking the C-terminal RING finger domain was confirmed by western blot analysis. |