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Allele : Mlh1<tm1Wed> mutL homolog 1; targeted mutation 1, Winfried Edelmann

Primary Identifier  MGI:3783409 Allele Type  Targeted
Gene  Mlh1 Transmission  Germline
Strain of Origin  STOCK 129/Sv and C57BL/6J and SJL Is Recombinase  false
Is Wild Type  false
molecularNote  Exon 2 was replaced with an exon 2 that contained a nucleotide substitution that resulted in an amino acid substitution of arginine for glycine at position 67 (G67R). This substitition occurs within the ATPase domain. A floxed neo cassette was also inserted into intron 1 but was subsequently removed by germ-line, cre-mediated recombination.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • Mlh1<G67R>,
  • Mlh1<G67R>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories