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Allele : Tg(Lck-Socs3)1Kubo transgene insertion 1, Masato Kubo

Primary Identifier	MGI:3783708	Allele Type	Transgenic
Attribute String	Inserted expressed sequence	Gene	Tg(Lck-Socs3)1Kubo
Is Recombinase	false	Is Wild Type	false

molecularNote

This transgene contains the Lck promoter with an Emu enhancer driving T-cell specific expression of a myc-tagged Socs3. Four identical lines were created and no line numbers were given. Expression of the myc-tagged transgene is 5 to 10 times higher than endogenous expression.

mutations:
Insertion

synonyms:
SOCS3 Tg,
SOCS3 Tg

earliestPublication:
Matsumoto A, et al. (2003) A role of suppressor of cytokine signaling 3 (SOCS3/CIS3/SSI3) in CD28-mediated interleukin 2 production. J Exp Med 197(4):425-36

1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

5 Publication categories

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