| Primary Identifier | MGI:3784951 | Allele Type | Targeted |
| Attribute String | Humanized sequence | Gene | Sgca |
| Transmission | Germline | Strain of Origin | 129S2/SvPas |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Exon 3 was replaced with an exon 3 that contained a nucleotide substitution that resulted in the amino acid substitution of cysteine for histidine at position 77 (H77C), mimicking a mutation associated with limb-girdle muscular dystrophy (LGMD2D) in human. A floxed neo cassette was inserted downstream of exon 3 and was subsequently removed by germ-line, cre-mediated recombination. |
