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Allele : Gt(ROSA)26Sor<tm1(CAG-Foxo1*)Jcbr> gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Jens C Bruning
Primary Identifier  MGI:3790725 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Gt(ROSA)26Sor
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  A transgene containing a Foxo1 cDNA with a truncation at amino acid position 256 followed by an IRES-GFP and driven by the CAGGS promoter (chicken beta actin promoter with CMV enhancers) was inserted into intron 1. An interviening floxed neo-STOP cassette prevents expression of the truncated Foxo1 cDNA except in the presence of cre when the floxed neo-STOP cassette is excised.
  • mutations:
  • Insertion
  • synonyms:
  • FOXO1<delta256>,
  • FOXO1<delta256>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories





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