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Allele : Nr1i2<tm1(NR1I2)Arte> nuclear receptor subfamily 1, group I, member 2; targeted mutation 1, TaconicArtemis

Primary Identifier  MGI:3790844 Allele Type  Targeted
Attribute String  Humanized sequence, Inserted expressed sequence, Null/knockout Gene  Nr1i2
Transmission  Germline Strain of Origin  C57BL/6
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 2 was replaced with a human cDNA encoding exons 2-4, intron 4, exon 5, intron 5, and fusion of exons 6-9 with an frt-flanked hygro cassette. The sequence was flanked by an attB53 site at the 5' end and an attP50 site at the 3' end. Germ line, flp mediated recombination was used to remove the hygro cassette. The absence of the endogenous transcript expression was confirmed by qPCR on liver and small intestine extracts.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • huPXR,
  • huPXR
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

0 Driven By

15 Publication categories