|  Help  |  About  |  Contact Us

Allele : Klrk1<tm1Dhr> killer cell lectin-like receptor subfamily K, member 1; targeted mutation 1, David H Raulet

Primary Identifier  MGI:3790957 Allele Type  Targeted
Attribute String  Null/knockout Gene  Klrk1
Transmission  Germline Strain of Origin  B6.Cg-Thy1<a>
Is Recombinase  false Is Wild Type  false
molecularNote  Exons 1b through exon 6 were replaced by a floxed neomycin resistance cassette through homologous recombination. Mice carrying germline mutations were crossed with a cre transgenic mouse strain to remove the neomycin selection cassette, leaving a single loxP site behind. Gene inactivation was confirmed by a lack of protein staining on NK cells using flow cytometry.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • NKG2D<->,
  • NKG2D<->
Quick Links:
 
Quick Links:
 

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

0 Driven By

33 Publication categories