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Allele : Upf2<tm1.1Btp> UPF2 regulator of nonsense transcripts homolog (yeast); targeted mutation 1.1, Bo Torben Porse
Primary Identifier  MGI:3790199 Allele Type  Targeted
Attribute String  Null/knockout Gene  Upf2
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  Exons 2 (containing the start methionine codon) and 3 were removed by germ line, cre mediated recombination. This allele is expected to produce a functionally inactive protein lacking several important domains including the N-terminal domain required for Upf1 interaction and nonsense-mediated mRNA decay (NMD).
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Upf2<delta>,
  • Upf2<delta>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories





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