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Allele : Isl1<tm1Gan> ISL1 transcription factor, LIM/homeodomain; targeted mutation 1, Lin Gan

Primary Identifier	MGI:3790243	Allele Type	Targeted
Attribute String	Null/knockout, Reporter	Gene	Isl1
Transmission	Germline	Strain of Origin	129S6/SvEvTac
Is Recombinase	false	Is Wild Type	false

molecularNote

The region between the initiation methionine condon in exon 1 through all of exon 2 was replaced with a lacZ cassette. Expression of LacZ was detected in amacrine cells of the retina.

mutations:
Insertion,
Intragenic deletion

cellLines:
Not Specified

synonyms:
Isl1<lacZ>,
Isl<lacZ>,
Isl1<lacZ>,
Isl<lacZ>

earliestPublication:
Elshatory Y, et al. (2007) Islet-1 controls the differentiation of retinal bipolar and cholinergic amacrine cells. J Neurosci 27(46):12707-20

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

10 Publication categories

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