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Allele : Gt(ROSA)26Sor<tm2(icre/ERT2)Jphe> gene trap ROSA 26, Philippe Soriano; targeted mutation 2, Jean-Paul Herman
Primary Identifier  MGI:3793441 Allele Type  Targeted
Attribute String  Inducible, Recombinase Gene  Gt(ROSA)26Sor
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Induced With  tamoxifen Is Recombinase  true
Is Wild Type  false
molecularNote  A humanized cre gene flanked by 2 tamoxifen-binding domains (ERT2-icre-ERT2) and followed by an frt-flanked hygro cassette was knocked into the locus. Inducible cre expression is present in all cells following treatment with tamoxifen with only the brain exhibiting decresed expression levels.
  • mutations:
  • Insertion
  • synonyms:
  • Cre2ERT2,
  • Gt(ROSA)26Sor<tm2(cre/ESR1)Jphe>,
  • Cre2ERT2,
  • ERT2-iCre-ERT2,
  • Gt(ROSA)26Sor<tm2(cre/ESR1)Jphe>,
  • ERT2-iCre-ERT2
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1 Feature

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0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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1 Driven By

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4 Publication categories

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