| Primary Identifier | MGI:3793462 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Rock2 |
| Transmission | Germline | Strain of Origin | Not Specified |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A neo cassette with a 3' loxP site was inserted downstream of exon 3 and an additional loxP site was inserted upstream of exon 3. Cre-mediated recombination in ES cells was used to remove the neo cassette and exon 3. The absence of protein product from the allele was confirmed by a 50% reduction in protein in heterozygotes as determined by western blot analysis on heart and kidney extracts. |