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Allele : Rock2<tm1.1Liao> Rho-associated coiled-coil containing protein kinase 2; targeted mutation 1.1, James K Liao

Primary Identifier  MGI:3793462 Allele Type  Targeted
Attribute String  Null/knockout Gene  Rock2
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  A neo cassette with a 3' loxP site was inserted downstream of exon 3 and an additional loxP site was inserted upstream of exon 3. Cre-mediated recombination in ES cells was used to remove the neo cassette and exon 3. The absence of protein product from the allele was confirmed by a 50% reduction in protein in heterozygotes as determined by western blot analysis on heart and kidney extracts.
  • mutations:
  • Insertion,
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

13 Publication categories

Trail: Allele