| Primary Identifier | MGI:3793421 | Allele Type | Transgenic |
| Attribute String | Reporter | Gene | Tg(CAG-EGFP/CETN2)3-4Jgg |
| Strain of Origin | BALB/c x C57BL/6 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The GFP-CETN2 transgene was designed with a chicken beta-actin promoter (with cytomegalovirus immediate early enhancer and beta-actin intron) upstream of an EGFP-centrin 2 fusion protein (containing the full length human centrin 2 cDNA cloned in-frame into the C-terminal of enhanced green fluorescent protein), and followed by a beta-globin polyA sequence. Two lines were maintained (18-1 and 3-4) and line 3-4 was donated to The Jackson Laboratory. These lines show consistent, robust expression of GFP in centrosomes (particularly in cerebellar granule cells). |
