Primary Identifier | MGI:3793714 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(Myh6*)131Lnwd |
Strain of Origin | (CBA x C57BL/6)F1 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | A rat myosin heavy chain promoter drives the expression of a rat cardiac alpha myosin heavy chain (Myh6) cDNA that was modified by mutating residue 1445 from a G to an A, and the deletion of codons 468-527. This resulted in a R403G substitution and a deletion in the putative actin binding domain in the encoded protein. This transgenic line exhibits a mild phenotype. |