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Allele : Tg(ACTA1-Ar)141Kyjo transgene insertion 141, Cynthia L Jordan

Primary Identifier	MGI:3794206	Allele Type	Transgenic
Attribute String	Inserted expressed sequence	Gene	Tg(ACTA1-Ar)141Kyjo
Strain of Origin	C4 x C57BL/6J	Is Recombinase	false
Is Wild Type	false

molecularNote

The human skeletal alpha-actin (HSA) promoter was used to drive expression of the rat Ar in skeletal muscles fibers. Seven lines were created with lines 78 (lower copy number) and 141 (higher copy number) characterized further for expression in skeletal muscle fibers.

mutations:
Insertion

synonyms:
HSA-AR,
HSA-AR

earliestPublication:
Monks DA, et al. (2007) Overexpression of wild-type androgen receptor in muscle recapitulates polyglutamine disease. Proc Natl Acad Sci U S A 104(46):18259-64

1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

12 Publication categories

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