Primary Identifier | MGI:3795216 | Allele Type | Targeted |
Attribute String | Hypomorph | Gene | Tpp1 |
Transmission | Germline | Strain of Origin | 129S1/Sv-Oca2<+> Tyr<+> Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The neo cassette was removed by germ line, cre-mediated recombination leaving the nucleotide substitution that results in the amino acid substitution of a histidine for an arganine at position 446 (Arg446His) intact. This allele is a hypomorph. |