Primary Identifier | MGI:3793787 | Allele Type | Targeted |
Gene | Hs6st1 | Transmission | Germline |
Strain of Origin | 129S6/SvEvTac | Is Recombinase | false |
Is Wild Type | false |
molecularNote | Germ line, cre mediated recombination was used to remove exon 1, which contains the start methionine codon and encodes the PAPs binding domain. RT-PCR confirmed weak expression of the truncated transcript that encodes a protein expected to have little enzymatic activity. |