Primary Identifier | MGI:3794650 | Allele Type | Targeted |
Gene | Wt1 | Transmission | Germline |
Strain of Origin | 129P2/OlaHsd-Hprt1<b-m3> | Is Recombinase | false |
Is Wild Type | false |
molecularNote | Exon 9 was replaced with one that contains an inserted Leu2/neo cassette that causes an amino acid substitution of arginine for serine at position 395 (S395R) and premature termination within the zinc finger 3 domain by inclusion of a translation stop codon at position 396. |