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Allele : Ppp4c<tm1.2Htn> protein phosphatase 4, catalytic subunit; targeted mutation 1.2, Shinji Hirotsune
Primary Identifier  MGI:3794751 Allele Type  Targeted
Attribute String  Null/knockout Gene  Ppp4c
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site was inserted in between exons 4 and 5. A floxed neomycin resistance cassette was inserted downstream of exon 8 and also replaced the codons of the last 4 amino acids of Tbx6. Cre-mediated recombination removed the selection cassette. Northern blot analysis confirmed normal Ppp4c transcript expression in embryo. RT-PCR confirmed normal Tbx6 transcript expression. Cre-mediated recombination removed the selection cassette and exons 5 through 8.
  • mutations:
  • Intergenic deletion
  • synonyms:
  • Tbx6/Ppp4c<tm1.2Htn>,
  • PP4c<->,
  • PP4c<->,
  • Tbx6/Ppp4c<tm1.2Htn>
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1 Feature

Trail: Allele

Genome

0 Expresses

2 Mutation Involves

Trail: Allele

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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