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Allele : Mael<tm1Bort> maelstrom spermatogenic transposon silencer; targeted mutation 1, Alex Bortvin
Primary Identifier  MGI:3795667 Allele Type  Targeted
Attribute String  Null/knockout Gene  Mael
Inheritance Mode  Recessive Transmission  Germline
Strain of Origin  (C57BL/6 x 129S4/SvJae)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  5.9 kb of genomic DNA encompassing the CpG island and first five exons of the gene were replaced with a loxP-flanked hygromycin-thymidine kinase selection cassette. Transient expression of cre recombinase in correctly targeted ES cells excised the selection cassette, leaving behind a single loxP site. Gene inactivation was confirmed by immunoblotting of testicular lysates.
  • mutations:
  • Insertion,
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

8 Publication categories

Trail: Allele




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