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Allele : Pik3cb<tm1.1Bvan> phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; targeted mutation 1.1, Bart Vanhaesebroeck

Primary Identifier	MGI:3795850	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Pik3cb
Transmission	Germline	Strain of Origin	129P2/OlaHsd
Is Recombinase	false	Is Wild Type	false

molecularNote

Germ line, cre-mediated recombination was used to remove exons 21 and 22. The absence of protein product was confirmed by immunobloting.

mutations:
Intragenic deletion

cellLines:
Not Specified

synonyms:
p110beta<(delta21,22>,
p110beta<(delta21,22>

earliestPublication:
Guillermet-Guibert J, et al. (2008) The p110beta isoform of phosphoinositide 3-kinase signals downstream of G protein-coupled receptors and is functionally redundant with p110gamma. Proc Natl Acad Sci U S A 105(24):8292-7

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

3 Carried By

0 Driven By

6 Publication categories

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