Primary Identifier | MGI:3796205 | Allele Type | Targeted |
Attribute String | Conditional ready, Inducible, Recombinase | Gene | Neurog3 |
Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
Induced With | tamoxifen | Is Recombinase | true |
Is Wild Type | false |
molecularNote | A cassette containing a floxed version of the open reading frame followed by a cre/ERT fusion gene was inserted to replace the endogenous gene. This allele expresses a normal Neurog3 protein unless exposed to Cre recombinase, which then causes recombination of the loxP sites and expression of the cre/ERT fusion. |