| First Author | Etxeberria A | Year | 2010 |
| Journal | Nat Neurosci | Volume | 13 |
| Issue | 3 | Pages | 287-289 |
| PubMed ID | 20173746 | Mgi Jnum | J:279520 |
| Mgi Id | MGI:6212604 | Doi | 10.1038/nn.2500 |
| Citation | Etxeberria A, et al. (2010) Adult-born SVZ progenitors receive transient synapses during remyelination in corpus callosum. Nat Neurosci 13(3):287-289 |
| abstractText | We found that demyelinated axons formed functional glutamatergic synapses onto adult-born NG2(+) oligodendrocyte progenitor cells (OPCs) migrating from the subventricular zone after focal demyelination of adult mice corpus callosum. This glutamatergic input was substantially reduced compared with endogenous callosal OPCs 1 week after lesion and was lost on differentiation into oligodendrocytes. Therefore, axon-oligodendrocyte progenitor synapse formation is a transient and regulated step that occurs during remyelination of callosal axons. |
