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Allele : Nrxn2<tm2Sud> neurexin II; targeted mutation 2, Thomas C Sudhof

Primary Identifier  MGI:3797418 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Nrxn2
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site was inserted into the 5' end of a modified exon 17, which contains an hemagglutinin (HA) reporter tag followed by a FRT-flanked neomycin resistance cassette and a loxP site. Flp-mediated recombination removed the selection cassette and left the modified exon 17 floxed. The HA insert does not affect the expression of neurexin 2 gene, but it is very difficult to detect GFP signals in the tissue by immunohistochemistry.
  • mutations:
  • Insertion
  • synonyms:
  • Nrxn2beta cKO,
  • Nrxn2beta cKO
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

16 Publication categories