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Allele : Nrxn3<tm2Sud> neurexin III; targeted mutation 2, Thomas C Sudhof

Primary Identifier  MGI:3797484 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Nrxn3
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site was inserted into the 5' end of a modified exon 17, which contains an EGFP reporter gene followed by a FRT-flanked neomycin resistance cassette and a loxP site. Flp-mediated recombination removed the selection cassette and left the modified exon 17 floxed. The GFP insert does not affect the expression of neurexin 3 gene, but it is very difficult to detect GFP signals in the tissue by immunohistochemistry or direct fluorescence.
  • mutations:
  • Insertion
  • synonyms:
  • Nrxn3beta cKO,
  • Nrxn3beta cKO
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

9 Publication categories

Trail: Allele