| Primary Identifier | MGI:3797070 | Allele Type | Chemically induced (ENU) |
| Attribute String | Hypomorph | Gene | Il7 |
| Inheritance Mode | Recessive | Strain of Origin | C57BL/6 |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | ENU mutagenesis led to a G-to-A point mutation in the splicing donor site of the third exon of the gene locus. This mutation resulted in skipping of exon 3 during transcription and production of a internally truncated transcript that potentially encodes a polypeptide that lacks sequence from aspartic acid-49 to lysine-75. RT-PCR confirmed the presence of a truncated mRNA. This is considered a hypomorph allele. |
