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Allele : Ccne1<tm1Clur> cyclin E1; targeted mutation 1, Bruce E Clurman

Primary Identifier	MGI:3797100	Allele Type	Targeted
Attribute String	Not Specified	Gene	Ccne1
Transmission	Germline	Strain of Origin	129S4/SvJae
Is Recombinase	false	Is Wild Type	false

molecularNote

A contruct carrying a threonine to alanine amino acid substitution at positions 74 and 393 was knocked into the locus. A floxed neo cassette used for selection was removed by germ line, cre-mediated recombination.

mutations:
Nucleotide substitutions,
Insertion

cellLines:
Not Specified

synonyms:
E<T74A T393A>,
E<T74A T393A>

earliestPublication:
Minella AC, et al. (2008) Cyclin E phosphorylation regulates cell proliferation in hematopoietic and epithelial lineages in vivo. Genes Dev 22(12):1677-89

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

8 Publication categories

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