Primary Identifier | MGI:3798768 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Kdm5a |
Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A targeting vector was generated by flanking exons 5 and 6 with a 5' loxP site and a 3' Frt-PGK-neomycin-Frt-LoxP expression cassette. Germline transmitting mice were bred sequentially with CAGG-Flpe mice to remove the neo cassette, and then to EIIa-Cre transgenic mice in FVB background to generate the null allele. |