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Allele : Tg(IgkHyHEL10)1Rbr transgene insertion 1, Robert Brink

Primary Identifier	MGI:3800384	Allele Type	Transgenic
Attribute String	Inserted expressed sequence	Gene	Tg(IgkHyHEL10)1Rbr
Strain of Origin	Not Specified	Is Recombinase	false
Is Wild Type	false

molecularNote

The HyHEL10 hybridoma produces an antibody that binds hen egg lysozyme peptide (HEL) with high affinity . The transgenic construct contained the recombined gene segments of the HyHEL10 kappa light chain (Igk). Expression of the transgene was detected in B cells

mutations:
Insertion

synonyms:
LC2 Ig,
LC2 Ig

earliestPublication:
Cook AJ, et al. (2003) Reduced switching in SCID B cells is associated with altered somatic mutation of recombined S regions. J Immunol 171(12):6556-64

1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

17 Publication categories

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