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Allele : Slc35d3<IAP> solute carrier family 35, member D3; intracisternal A particle insertion

Primary Identifier  MGI:3802578 Allele Type  Spontaneous
Gene  Slc35d3 Strain of Origin  C3H/HeSn-Rab27a<ash>/JRos
Is Recombinase  false Is Wild Type  false
molecularNote  468 bp of endogenous sequence in exon 1 was replaced with a 39 bp intracisternal A particle (IAP) sequence resulting in a new translation initiation methionine codon and substitution of 7 new amino acids for 10 endogenous amino acids at the N-terminus (MRQLCRGRVL becomes MWGRLPT). No gain of function effect is observed as in other spontaneous mutations derived from IAP insertion.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Roswell,
  • Roswell,
  • Slc35d3<->,
  • Slc35d3<ros>,
  • Slc35d3<->,
  • Slc35d3<ros>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories

Trail: Allele