Primary Identifier | MGI:3805878 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(MC1R)1Jkn |
Strain of Origin | Not Specified | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The transgene strain was created by microinjection of the human BAC RPCI11-566K11 into embryos homozygous for Mc1re. The BAC contains 146 kb of sequence with the complete human gene MC1R and includes at least 4 other genes. Quantitative RT-PCR on skin samples indicated that expression of the human MC1R was 9- to 20-fold lower than the endogenous mouse gene. |