| Primary Identifier | MGI:3803949 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Fli1 |
| Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A floxed neo cassette was inserted into exon 9 via homologous recombination resulting in a premature stop codon between the DNA-binding domain and the CTA domain. The neo cassette was removed by germ line, cre-mediated recombination. Removal of the C-terminal domain results in a 40% to 50% reduction in transcriptional activation activity and the production of a truncated protein. |
