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Allele : Napepld<tm1.1Rpa> N-acyl phosphatidylethanolamine phospholipase D; targeted mutation 1.1, Richard D Palmiter

Primary Identifier  MGI:3804925 Allele Type  Targeted
Attribute String  Null/knockout Gene  Napepld
Transmission  Germline Strain of Origin  129S4/SvJaeSor
Is Recombinase  false Is Wild Type  false
molecularNote  LoxP sites flank exon 3. An Sv-Neo (SV40 promoter-neomycinphosphotransferase) gene is flanked by frt sites from removal by the action of FLPase. After removal of the Sv-Neo cassette by breeding with FLPer mice, exon 3 was removed in all cells by breeding with Mox2-Cre mice to generate heterozygous animals with one null NAPE-PLD allele. These mice were bred with C57BL/6 mice to remove the Mox2-Cre gene, and then bred together to generate mice homozygous for the NAPE-PLD-null allele.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • NAPE-PLD<->,
  • NAPE-PLD<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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6 Publication categories

Trail: Allele