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Allele : E2f3<tm2.1Gle> E2F transcription factor 3; targeted mutation 2.1, Gustavo Leone

Primary Identifier  MGI:3806814 Allele Type  Targeted
Attribute String  Null/knockout Gene  E2f3
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  A floxed neo cassette was inserted 108 bp upstream of the E2f3a start codon and a third loxP site was inserted approximately 300 bp downstream of exon 1a. In vivo cre-mediated recombination removed the neo cassette and exon 1a. Western blot analysis of MEFs confirmed the absence of expression of the E2f3a isoform with retention of expression of the E2f3b isoform.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • E2f3a<->,
  • E2f3a<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

8 Publication categories