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Allele : E2f3<tm3.1Gle> E2F transcription factor 3; targeted mutation 3.1, Gustavo Leone

Primary Identifier  MGI:3806817 Allele Type  Targeted
Attribute String  Null/knockout Gene  E2f3
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  A floxed neo cassette was inserted about 800 bp upstream of exon 1b and a third loxP site was inserted approximately 1.8 kp downstream of exon 1b. In vivo cre-mediated recombination removed the neo cassette and exon 1b. Western blot analysis of MEFs confirmed the absence of expression of the E2f3b isoform with retention of expression of the E2f3a isoform.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • E2f3b<->,
  • E2f3b<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

7 Publication categories