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Allele : Fscn2<ahl8> fascin actin-bundling protein 2; age related hearing loss 18

Primary Identifier  MGI:3807774 Allele Type  Spontaneous
Gene  Fscn2 Inheritance Mode  Recessive
Strain of Origin  DBA/2J Is Recombinase  false
Is Wild Type  false
description  ahl8 interacts with Cdh23 on chromosome 10.
molecularNote  G to A transition located in exon 1 and is of predicted to cause a nonsynonymous amino acid change of arginine to histidine at position 109 (R109H). The known genealogy of the DBA-related strains and genotyping analysis of archived DBA/2J DNA samples indicate that this allele occurred in the DBA/2J lineage between 1951 (when it was separated from the DBA/2N lineage) and 1975.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • Fscn2<R109H>,
  • Fscn2<R109H>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

0 Driven By

10 Publication categories