|  Help  |  About  |  Contact Us

Allele : Als2<tm1Garo> alsin Rho guanine nucleotide exchange factor; targeted mutation 1, Guy A Rouleau

Primary Identifier  MGI:3807480 Allele Type  Targeted
Attribute String  Modified isoform(s) Gene  Als2
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A neo cassette replaced exon 2 and part of exon 3 via homologous recombination. Immunoblot blot analysis confirmed the absence of full length protein in brains from homozygous mice. However, immunoblot and RT-PCR analysis detect the presence of other Als2 isoforms in neurons.
  • mutations:
  • Intragenic deletion,
  • Insertion
Quick Links:
 
Quick Links:
 

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories