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Allele : Nfasc<tm1.1Brp> neurofascin; targeted mutation 1.1, Peter J Brophy

Primary Identifier  MGI:3808598 Allele Type  Targeted
Attribute String  Null/knockout Gene  Nfasc
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site was inserted upstream of exon 4 and a floxed neo cassette downstream of exon 4. Transient cre expression in ES cells was used to remove the neo cassette and exon 4. The absence of protein expression was confirmed by western blot analysis on sciatic nerve extracts.
  • mutations:
  • Intragenic deletion,
  • Insertion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

13 Publication categories